Explores the changing roles, ethical conflicts, and public perceptions of science and scientists in American society from World War II to the present. Studies specific historical episodes focusing on debates between scientists and the contextual factors influencing their opinions and decisions. Topics include the atomic bomb project, environmental controversies, the Challenger disaster, biomedical research, genetic engineering, (mis)use of human subjects, scientific misconduct and whistleblowing.

The Anatomy Quizbook is an interactive learning book that will help students and tutors – indeed anyone interested in anatomy – learn, test and improve their knowledge of the human body.

Readers are presented with carefully selected questions and diagrams addressing core learning in clinically-relevant anatomy. This selective rather than exhaustive approach will especially suit time-poor scholars. Regular self-testing will also ensure a robust and strategic understanding of the subject matter.

In this first Volume, you can develop your knowledge of fundamental anatomy, including clinically-relevant terminology and the significant parts and operation of the:

- Thorax, focusing on the heart, lungs, and associated bones, muscles, nerves, blood and lymphatic vessels.

- Abdomen, exploring the stomach, intestines, pancreas, liver, gallbladder, kidneys, spleen and their supporting structures (muscles, nerves, blood and lymphatic vessels).

- Pelvis, examining the bones, ligaments, vessels and nerves of the pelvic region, the features of male and female pelves, and the major digestive and excretory organs (colon, rectum, bladder and urethra).

Whilst developed primarily for students who are studying, or intend to study, medicine, the Anatomy Quizbook will reward all readers who seek to explore and learn about the workings of the human body.

Regular users will find much to learn and build on, hopefully leading to further enthusiasm for a valuable subject that underpins much of medicine.

" This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers."

This course presents the fundamentals of digital signal processing with particular emphasis on problems in biomedical research and clinical medicine. It covers principles and algorithms for processing both deterministic and random signals. Topics include data acquisition, imaging, filtering, coding, feature extraction, and modeling. The focus of the course is a series of labs that provide practical experience in processing physiological data, with examples from cardiology, speech processing, and medical imaging. The labs are done on the MIT Server in MATLABĺ¨ during weekly lab sessions that take place in an electronic classroom. Lectures cover signal processing topics relevant to the lab exercises, as well as background on the biological signals processed in the labs.

This course has been designed as a seminar to give students an understanding of how scientists with medical or scientific degrees conduct research in both hospital and academic settings. There will be interactive discussions with research clinicians and scientists about the career opportunities and research challenges in the biomedical field, which an MIT student might prepare for by obtaining an MD, PhD, or combined degrees. The seminar will be held in a case presentation format, with topics chosen from the radiological sciences, including current research in magnetic resonance imaging, positron emission tomography and other nuclear imaging techniques, and advances in radiation therapy. With the lectures as background, we will also examine alternative and related options such as biomedical engineering, medical physics, and medical engineering. We'll use as examples and points of comparisons the curriculum paths available through MIT's Department of Nuclear Science and Engineering. In past years we have given very modest assignments such as readings in advance of or after a seminar, and a short term project.

In this 11-minute video lesson Sal makes random predictions for the year 2060. [Cosmology and Astronomy playlist: Lesson 85 of 85]

D-Lab Health provides a multidisciplinary approach to global health technology design via guest lectures and a major project based on fieldwork. We will explore the current state of global health challenges and learn how to design medical technologies that address those problems. Students may travel to Nicaragua during spring break to work with health professionals, using medical technology design kits to gain field experience for their device challenge. As a final class deliverable, you will create a product design solution to address challenges observed in the field. The resulting designs are prototyped in the summer for continued evaluation and testing.

" This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants."

This course examines the growing importance of medicine in culture, economics and politics. It uses an historical approach to examine the changing patterns of disease, the causes of morbidity and mortality, the evolution of medical theory and practice, the development of hospitals and the medical profession, the rise of the biomedical research industry, and the ethics of health care in America.

First aid is the provision of immediate care to a victim with an injury of illness, usually effected by a lay person, and performed within a limited skill range. First aid is normally performed until the injury or illness is satisfactorily dealt with (such as in the case of small cuts, minor bruises, and blisters) or until the next level of care, such as an ambulance or doctor, arrives. This book is a Canadian version of the original at Wikibooks. All references to protocols which do not comply with resuscitation standards in Canada have been removed.

GEM4 VisionGEM4 has brought together researchers and professionals in major institutions across the globe with distinctly different, but complementary, expertise and facilities to address significant problems at the intersections of select topics of engineering, life sciences, technology, medicine and public health.GEM4 creates new models for interactions across scientific disciplinary boundaries whereby problems spanning the range of fundamental science to clinical studies and public health can be addressed on a global scale through strategic international partnerships.Through initial focus areas in cell and molecular biomechanics, and environmental health, in the context of select human diseases, GEM4 creates a global forum for the definition and exploration of grand challenges and scientific studies, for the cross-fertilization of ideas among engineers, life scientists and medical professionals, and for the development of novel educational tools.GEM4 ActivitiesGEM4 enables the brokering of engineers, life scientists and medical professionals with shared facilities and joint students and post-doctoral fellows to tackle major problems in the context of human health and diseases that call for state-of-the-art experimental and computational tools in cell and molecular mechanics, biology and medicine. Broad examples of problems addressed include:infectious diseases such as malaria,cancer,cardiovascular diseases,biomechanical origins of inflammation.In each of these areas, the initial emphasis has included (but will not be limited to) molecular, subcellular and cellular mechanics applied to biomedicine, where a single investigator or institution is not likely to have the full spectrum of expertise, infrastructure or resources available to cover fundamental molecular science all the way to clinical studies and societal implications. Currently, twelve institutions in North America, Europe and Asia participate in this effort as Core institutions, focusing on mechanistic studies, as well as novel methods for diagnostics, vaccines or drug development and delivery.Funds have been raised to provide a structure for coordinated studies from major organizations under the umbrella of GEM4. These funds are being used for:organization of major symposia/conferences specifically targeted at the theme areas of the initiative,training grants for student fellowships for the partner institutions,summer schools to develop teaching materials,the exchange of students and researchers,operations of a central secretariat for handling the administrative and infrastructure details for such interactions,maintenance of a web site for dissemination of information.

Examines the development of computing techniques and technology in the nineteenth and twentieth centuries, particularly critical evaluation of how the very idea of "computer" changes and evolves over time. Emphasis is on technical innovation, industrial development, social context, and the role of government. Topics include Babbage, Hollerith, differential analyzers, control systems, ENIAC, radar, operations research, computers as scientific instruments, the rise of "computer science," artificial intelligence, personal computers, and networks. Includes class visits by members of the MIT community who have made important historical contributions. This course focuses on one particular aspect of the history of computing: the use of the computer as a scientific instrument. The electronic digital computer was invented to do science, and its applications range from physics to mathematics to biology to the humanities. What has been the impact of computing on the practice of science? Is the computer different from other scientific instruments? Is computer simulation a valid form of scientific experiment? Can computer models be viewed as surrogate theories? How does the computer change the way scientists approach the notions of proof, expertise, and discovery? No comprehensive history of scientific computing has yet been written. This seminar examines scientific articles, participants' memoirs, and works by historians, sociologists, and anthropologists of science to provide multiple perspectives on the use of computers in diverse fields of physical, biological, and social sciences and the humanities. We explore how the computer transformed scientific practice, and how the culture of computing was influenced, in turn, by scientific applications.

"This innovative, trans-faculty subject teaches how information technologies (IT) are reshaping and redefining the health care marketplace through improved economies of scale, greater technical efficiencies in the delivery of care to patients, advanced tools for patient education and self-care, network integrated decision support tools for clinicians, and the emergence of e-commerce in health care. Student tutorials provide an opportunity for interactive discussion. Interdisciplinary project teams comprised of Harvard and MIT graduate students in medicine, business, law, education, engineering, computer science, public health, and government collaborate to design innovative IT applications. Projects are presented during the final class. ĺĘ Starting in Spring 2010, this course will be titled Enabling Technology Innovation in Healthcare and the Life Sciences."

Introduction to Sociology 2e adheres to the scope and sequence of a typical, one-semester introductory sociology course. It offers comprehensive coverage of core concepts, foundational scholars, and emerging theories, which are supported by a wealth of engaging learning materials. The textbook presents detailed section reviews with rich questions, discussions that help students apply their knowledge, and features that draw learners into the discipline in meaningful ways. The second edition retains the book’s conceptual organization, aligning to most courses, and has been significantly updated to reflect the latest research and provide examples most relevant to today’s students. In order to help instructors transition to the revised version, the 2e changes are described within the preface.

A textbook which can be used for the field of Laboratory Medicine and Pathology, featuring digitized scans of laboratory slides which enables students to learn clinical hematology without access to a laboratory.

An exploration of colonial and postcolonial clashes between theories of healing and embodiment in the African world and those of western bio-medicine. Examines how Afro-Atlantic religious traditions have challenged western conceptions of illness, healing, and the body, and have offered alternative notions of morality, rationality, kinship, gender and sexuality. Analyzes whether contemporary western bio-medical interventions reinforce colonial or imperial power in the effort to promote global health in Africa and the African diaspora.

Medicines By Design aims to explain how scientists unravel the many different ways medicines work in the body and how this information guides the hunt for drugs of the future. Pharmacology is a broad discipline encompassing every aspect of the study of drugs, including their discovery and development and the testing of their action in the body. Much of the most promising pharmacological research going on at universities across the country is sponsored by the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH), U.S. Department of Health and Human Services. Working at the crossroads of chemistry, genetics, cell biology, physiology, and engineering, pharmacologists are fighting disease in the laboratory and at the bedside.

The eight-session subject uses literary narratives and poetry to study ethical issues in medicine. Methodology emphasizes the importance of context, contingency, and circumstance in recognizing, evaluating, and resolving moral problems. Focus on developing the skills of critical and reflective reading that increase effectiveness in clinical medicine. Texts include short fiction and poetry by Woolf, Chekhov, Carver, Kafka, Hurston, Marquez, and Tolstoy. Instructor provides necessary philosophic and literary context followed by class discussion. Students keep a reading journal that examines the meanings of illness, the moral role of the physician, and the relevance of emotions, culture, faith, values, social realities, and life histories to patient care.

Neuroscience for Pre-Clinical Students covers neuroenergetics, neurotransmitters, neuropeptides, and selected amino acid metabolism and degradation. This USMLE-aligned text is designed for a first-year undergraduate medical course and is meant to provide the essential biochemical information from these content areas in a concise format to enable students to engage in an active classroom. Hence, it does not cover neurophysiology and neuroanatomy; and clinical correlates and additional application of content are intended to be provided in the classroom experience. The text assumes that the students will have completed medical school prerequisites (including the MCAT) in which they will have been introduced to the most fundamental concepts of biology and chemistry that are essential to understand the content presented here. With its focus on high-yield concepts, this resource will assist the learner later in medical school and for exam preparation.

The 49-page text was created specifically for use by pre-clinical students at Virginia Tech Carilion School of Medicine and was based on faculty experience and peer review to guide development and hone important topics.

Available Formats
ISBN 978-1-949373-80-6 (PDF)
ISBN 978-1-949373-81-3 (ePub) [coming soon]
ISBN 978-1-949373-84-4 (print) [coming sooon]
ISBN 978-1-949373-82-0 (Pressbooks) https://pressbooks.lib.vt.edu/neuroscience
Also available via LibreTexts: https://med.libretexts.org/@go/page/35685

How to Adopt this Book
Instructors reviewing, adopting, or adapting parts or the whole of the text are requested to register their interest at: https://bit.ly/interest-preclinical.

Instructors and subject matter experts interested in and sharing their original course materials relevant to pre-clinical education are requested to join the instructor portal at https://www.oercommons.org/groups/pre-clinical-resources/10133.

Features of this Book
1. Detailed learning objectives are provided at the beginning of each subsection;
2. High resolution, color contrasting figures illustrate concepts, relationships, and processes throughout;
3. Summary tables display detailed information;
4. End of chapter lists provide additional sources of information; and
5. Accessibility features including structured heads and alternative-text provide access for readers accessing the work via a screen-reader.

Table of Contents
1. Neuron and astrocyte metabolism
2. Neurotransmitters — ACh, glutamate, GABA, and glycine
3. Neuropeptides and unconventional neurotransmitters
4. Amino acid metabolism and specialized products

Suggested Citation
LeClair, Renée J., (2022). Neuroscience for Pre-Clinical Students, Blacksburg, VA: Virginia Tech Publishing. https://doi.org/10.21061/neuroscience. Licensed with CC BY NC-SA 4.0.

About the Author
Renée J. LeClair is an Associate Professor in the Department of Basic Science Education at the Virginia Tech Carilion School of Medicine, where her role is to engage activities that support the departmental mission of developing an integrated medical experience using evidence-based delivery grounded in the science of learning. She received a Ph.D. at Rice University and completed a postdoctoral fellowship at the Maine Medical Center Research Institute in vascular biology. She became involved in medical education, curricular renovation, and implementation of innovative teaching methods during her first faculty appointment, at the University of New England, College of Osteopathic Medicine. In 2013, she moved to a new medical school, University of South Carolina, School of Medicine, Greenville. The opportunities afforded by joining a new program and serving as the Chair of the Curriculum committee provided a blank slate for creative curricular development and close involvement with the accreditation process. During her tenure she developed and directed a team-taught student-centered undergraduate medical course that integrated the scientific and clinical sciences to assess all six-core competencies of medical education.

Accessibility Note
The University Libraries at Virginia Tech and Virginia Tech Publishing are committed to making its publications accessible in accordance with the Americans with Disabilities Act of 1990. The HTML (Pressbooks) and ePub versions of this book utilize header structures and include alternative text which allow for machine-readability.

Please report any errors at https://bit.ly/feedback-preclinical

Principles of tomographic imaging using ionizing and non-ionizing radiation, and ultrasound. Emphasis is placed on fundamental physics and mathematics involved in image formation, including basic interactions, data acquisition and reconstruction. Planar radiographic imaging, multi-dimensional tomography (X-ray CAT, PET, SPECT), ultrasound, and NMR imaging covered. 22.56J aims to give graduate students and advanced undergraduates background in the theory and application of noninvasive imaging methods to biology and medicine, with emphasis on neuroimaging. The course focuses on the modalities most frequently used in scientific research (X-ray CT, PET/SPECT, MRI, and optical imaging), and includes discussion of molecular imaging approaches used in conjunction with these scanning methods. Lectures by the professor will be supplemented by in-class discussions of problems in research, and hands-on demonstrations of imaging systems.