Anatomy and Physiology is a dynamic textbook for the two-semester human anatomy and physiology course for life science and allied health majors. The book is organized by body system and covers standard scope and sequence requirements. Its lucid text, strategically constructed art, career features, and links to external learning tools address the critical teaching and learning challenges in the course. The web-based version of Anatomy and Physiology also features links to surgical videos, histology, and interactive diagrams.

Human Anatomy and Physiology (A&P) 242 is the second class in a two quarter sequence in which human anatomy and physiology are studied using a body systems approach with emphasis on the interrelationships between form and function at the gross and microscopic levels of organization. You can think of this course as “An Owner’s Guide to the Human Body”. My goal is to help you learn how your body works so that you can explain concepts to others and apply knowledge to novel situations (e.g. make informed decisions regarding your own health and those whom you care about). You’ll also learn how to evaluate scientific research that forms the basis of our understanding of human anatomy and physiology and gain an appreciation for what remains to be discovered. To accomplish these goals requires significant effort from both of us. Although you will need to commit information to memory, I will ask you to focus on learning for understanding and your assessments will reflect this emphasis.

You will also gain experience problem solving, interpreting data, communicating verbally and in writing with others, developing information literacy skills, using technology and exploring how your knowledge of anatomy and physiology can be applied to real world health challenges. This course is designed to build the core knowledge and skills needed to succeed in a world that demands flexibility and continuous learning and to prepare you for advanced study of anatomy, physiology and clinically-related subjects.

" This course does not seek to provide answers to ethical questions. Instead, the course hopes to teach students two things. First, how do you recognize ethical or moral problems in science and medicine? When something does not feel right (whether cloning, or failing to clone) ‰ŰÓ what exactly is the nature of the discomfort? What kind of tensions and conflicts exist within biomedicine? Second, how can you think productively about ethical and moral problems? What processes create them? Why do people disagree about them? How can an understanding of philosophy or history help resolve them? By the end of the course students will hopefully have sophisticated and nuanced ideas about problems in bioethics, even if they do not have comfortable answers."

Students will learn about the use of biomaterials to create advanced diagnostic tools for detection of infectious and chronic diseases, restore insulin production to supplement lost pancreatic function in diabetes, provide cells with appropriate physical, mechanical, and biochemical cues to direct tissue regeneration, and enhance the efficacy of cancer immunotherapy.

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

By Emily Hooker and Sarah Pressman, University of North Carolina at Chapel Hill, University of Calfornia, Irvine. Our emotions, thoughts, and behaviors play an important role in our health. Not only do they influence our day-to-day health practices, but they can also influence how our body functions. This module provides an overview of health psychology, which is a field devoted to understanding the connections between psychology and health. Discussed here are examples of topics a health psychologist might study, including stress, psychosocial factors related to health and disease, how to use psychology to improve health, and the role of psychology in medicine.

This course addresses the challenges of defining a relationship between exposure to environmental chemicals and human disease. Course topics include epidemiological approaches to understanding disease causation; biostatistical methods; evaluation of human exposure to chemicals, and their internal distribution, metabolism, reactions with cellular components, and biological effects; and qualitative and quantitative health risk assessment methods used in the U.S. as bases for regulatory decision-making. Throughout the term, students consider case studies of local and national interest.

D-Lab Health provides a multidisciplinary approach to global health technology design via guest lectures and a major project based on fieldwork. We will explore the current state of global health challenges and learn how to design medical technologies that address those problems. Students may travel to Nicaragua during spring break to work with health professionals, using medical technology design kits to gain field experience for their device challenge. As a final class deliverable, you will create a product design solution to address challenges observed in the field. The resulting designs are prototyped in the summer for continued evaluation and testing.

This course examines the growing importance of medicine in culture, economics and politics. It uses an historical approach to examine the changing patterns of disease, the causes of morbidity and mortality, the evolution of medical theory and practice, the development of hospitals and the medical profession, the rise of the biomedical research industry, and the ethics of health care in America.

Immune cells protect our bodies from both self-derived threats and exogenous pathogens, while keeping peace with normal cells and non-harmful commensal microbiota. They have various mechanisms to perform these tasks, a capacity that is essential for maintaining homeostasis. However, these same mechanisms can backfire, resulting in severe disorders such as immunodeficiency, chronic inflammation, allergy, degenerative diseases, and cancer. This course discusses the connections between normal physiology and disease by examining the developmental relationship between innate and adaptive immune cells as well as the functions and malfunctions of immune cells. The course familiarizes students with both basic biological principles (such as cell death and immune cell signaling) and clinical applications (such as immune checkpoint blockade). More generally, students learn to identify relevant primary research literature, critically evaluate experimental data, and reach their own conclusions based on primary data.

This multidisciplinary seminar addresses fundamental issues in global health faced by community-based healthcare programs in developing countries. Students will broadly explore topics with expert lecturers and guided readings. Topics will be further illuminated with case studies from healthcare programs in urban centers of Zambia. Multidisciplinary teams will be formed to develop feasible solutions to specific health challenges posed in the case studies and encouraged to pursue their ideas beyond the seminar. Possible global health topics include community-based AIDS/HIV management, maternity care, health diagnostics, and information technology in patient management and tracking. Students from Medicine, Public Health, Engineering, Management, and Social Sciences are encouraged to enroll. No specific background experience is expected, but students should have some relevant skills or experiences.

This book is intended to provide a basic introduction to epidemiologic methods and epidemiologic thinking. After reading this book, you should be able to read an epidemiologic study, understand what the authors did and why, and identify what they found. You will also have the tools to assess the quality of that study—how good is the evidence? What are potential sources of bias, and how might those have affected the results? This book will not teach you enough to be able to design and conduct your own epidemiologic studies—that level of understanding requires several years of specialized training. However, being able to read and understand the scientific literature about human health will allow you to apply that understanding to your own work in a nuanced, sophisticated way.

Readers will learn about the nature of health, health education, health promotion and related concepts. This will help to understand the social, psychological and physical components of health.

This virtual simulation promotes the application of knowledge and skills related to interprofessional collaboration and infection prevention and control practices. Learners will need a foundational knowledge in infection prevention and control practices, including routine practices and additional precautions guidelines. Learners will use their assessment and communication skills throughout the game. By the end of the virtual gaming simulation, learners will be able to apply interprofessional communication skills to foster collaboration and provide safe client care, demonstrate knowledge and skills related to infection prevention and control practices, and identify high risk areas to break the chain of transmission.

This course presents a unique and challenging perspective on the causes of human disease and mortality. The course focuses on analyses of major causes of mortality in the US since 1900: cancer cardiovascular and cerebrovascular diseases, diabetes, infectious diseases. Students create analytical models to derive estimates for historically variant population risk factors and physiological rate parameters, and conduct analyses of familial data to separately estimate inherited and environmental risks. The course evaluates the basic population genetics of dominant, recessive and non-deleterious inherited risk factors.

" This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics."

This courses focuses on the fundamentals of tissue and organ response to injury from a molecular and cellular perspective. There is a special emphasis on disease states that bridge infection, inflammation, immunity, and cancer. The systems approach to pathophysiology includes lectures, critical evaluation of recent scientific papers, and student projects and presentations. This term, we focus on hepatocellular carcinoma (HCC), chronic-active hepatitis, and hepatitis virus infections. In addition to lectures, students work in teams to critically evaluate and present primary scientific papers.

Quantitative Ecology introduces and discusses the principles of ecology from populations to ecosystems including human populations, disease, exotic organisms, habitat fragmentation, biodiversity and global dynamics. The book also reformulates and unifies ecological equations making them more accessible to the reader and easier to teach.

An open source textbook designed and written by the students of HMB422 Topics in Health & Disease!